Science and Research

Early Respiratory Impairment and Pneumonia after Hybrid Laparoscopically Assisted Esophagectomy-A Comparison with the Open Approach

Patients undergoing esophageal cancer surgery are at high risk of developing severe pulmonary complications. Beneficial effects of minimally invasive esophagectomy had been discussed recently, but the incidence of perioperative respiratory impairment remains unclear. This is a retrospective single-center cohort study of patients, who underwent open (OE) or laparoscopically assisted, hybrid minimally invasive abdomino-thoracic esophagectomy (LAE) for cancer regarding respiratory impairment (PaO2/FiO2 ratio (P/FR) < 300 mmHg) and pneumonia. No differences were observed in the cumulative incidence of reduced P/FR between OE and LAE patients. Of note, until postoperative day (POD) 2, P/FR did not differ among both groups. Thereafter, the rate of patients with respiratory impairment was higher after OE on POD 3, 5, and 10 (p
  • Reichert, M.
  • Lang, M.
  • Hecker, M.
  • Schneck, E.
  • Sander, M.
  • Uhle, F.
  • Weigand, M. A.
  • Askevold, I.
  • Padberg, W.
  • Grau, V.
  • Hecker, A.
  • Keywords

    • Horovitz index
    • Ivor Lewis esophagectomy
    • abdomino-thoracic esophagectomy
    • lung injury
    • oxygenation
    • pneumonia
    • pulmonary function
    • pulmonary function index
    • respiratory complication
    • vagal nerve
    Publication details
    DOI: 10.3390/jcm9061896
    Journal: J Clin Med
    Number: 6
    Work Type: Original
    Location: TLRC, UGMLC
    Disease Area: LC, PALI
    Partner / Member: JLU, UKHD
    Access-Number: 32560416
    See publication on PubMed

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